My husband was told he needs B12 injections today


My husband was told he needs B12 injections today. Now, he eats plenty meat, and eggs. ( no liver )
What could account for a low level? He was only told that 150 is normal and he was below 111. No specific number given. Any insights? Thank you in advance.

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Win 3 years 0 Answers 443 views 0

Answers ( No )

  1. Medications can impact absorption of b12 – diabetic meds, antacids, PPIs, as well as auto immune factors

  2. Has he been tested for pernicious anaemia… He could have trouble absorbing B12.. Chrons and coeliac may also make absorption an issue… Has he had any investigative work..? He may need to go and see a GI

  3. yes so many medications can deplete one of B12…alcohol too…look at list of medications, including over the counter…we are not sure why, but Miralax creates extremely high unexplainable B12 levels circulating, but we are not sure kids are absorbing…

  4. Any dental work lately? Nitrous oxide depletes B12 like crazy!

  5. No, just teeth cleaning !

  6. Low B12 is generally caused by a deficiency of Intrinsic Factor in the stomach which is an auto immune disorder. Even if you give oral B12, it will be difficult to absorb and large amounts will be required. That is why your doctor suggested B12 injections.

  7. And yes, he is on a fair bit of meds, warfarin daily and other meds , all prescribed to prevent blood clots occurring of which he nearly died twice. He was diagnosed 2 years ago with an autoimmune disease called Church and Straus. Told now he is in remission. He also takes meds for thyroid and bronchial issues and other meds.
    Just writing this down makes me shutter and I drive myself to drinking attempting to inform him . nattering at him Next Dr visit he will finally ask what the purpose is for all these meds to continue and see what can be eliminated!
    What a struggle! I am so anti conventional medicine and he is riding the dragon!

  8. Possible mutations making it hard for him to absorb it from food? I found out a year ago that that is my problem with b12 and folate.

  9. That is a VERY low B12. EVen the 150 would lead to many symptomatic people. There are many reasons someone might be low. It's very common and under diagnosed. A shame. It's cheap and safe to treat but deficiency can be deadly. Many countries have crazy-low B12 ranges unfortunately. He will need adequate folate to use the B12 that is injected. Serum is not the best way to judge levels unfortunately. Once supplementing, there's no point testing. The British Formulary says as much.

  10. IMHO, I think as many people who are deficient in Magnesium are also probably deficient in B12. Not sure if there is a connection, but pretty much everyone who is hypothyroid will be B12 deficient. Also, know that the lab ranges are PITIFULLY low for this nutrient. Good levels should be up around 800 or more.

    Of course, stomach acid kills B12, so either injection or sublingual is the only way to go. Doing sublingually will take time to get it up. If really low, probably need injections.

    But thinking this through, B12 is dependent on iron levels being good. What makes iron levels good? CERULOPLASMIN! So if you can get Cp up and iron levels and Saturation % up, then B12 is likely to follow if being supplemented with liver and sublingual.

    Here is a great brand, cheap and easy to do, and tastes good!

  11. Mthfr gene mutation, MTRR gene mutation are common mutations (could be others) related to low B12 and both effected by low Magnesium. Magnesium is a big player in methylation, as are B vitamins and other minerals.

    Other issues to consider are poor cell wall fluidity with B12 not being absorbed (Lithium Orotate) would help.

    Gut issues.

  12. Win, Sorry, I had not read the earlier posts. So yes, his B12 IS low. Injections weekly are going to be the only way to bring levels up. Agree with the article posted by you. We get a vial of 10 ml of methylcobalamin about every 6 weeks and hubby and I both take a weekly injection. I give his to him and do my own. It's easy to learn once you get over the fact you have to just stab that needle in there and get it over with.

    But the other facet is what other posters have said about genetic mutations. I know nothing about that, never having had a genetic pathway test done. The methylcobalamin B12 worked well for us from the start, so we were good because it did bring our levels up. Learning your genetic mutation pathways WILL help determine WHICH form of cobalamin to take; cyano, methyl, etc.

    Gut issues are not in play if you use injections though.

    The book, "Could it be B12" is a good book. But getting the right type of B12 injectable and doing injections weekly will make him feel so much better.

  13. Lots of great info here at this info hub website run by Tracey Witty.

  14. Also for anyone in the UK wanting to know more about B12 and methylation … you might like to know about the not for profit conference at Loughborough University in June. Sally Pacholok is speaking

  15. Can B12 deficiency cause weight loss?

  16. Remember that there are four types of B12. Some may show no improvement for him.

    I had the shots monthly for over a year with no benefit.
    When I switched to bee pollen plus sublingual methyl B12, Wow! what a difference.

  17. Win, you or your husband may wish to join the Pernicious Anemia/B12 Deficiency FB group. Lots of great info on tests, levels, co-factors etc.

  18. Win Konijn – have your husband get the recommended testing done.

  19. Win Konijn, you have received a lot of info to digest and a lot of it is on the mark. At least one person has touched MTHFR and another on gut issues.

    You need to know that all the shots – in the USA – are cyanocobolamin. If there's a genetic defect, the body can't replace the cyanide atom with a methyl group and the body can't use it. The levels will go up but he won't feel better.

    The way around this is to take methylcobolamin sublingually. This gets it directly into the blood bypassing any gut issues. It's advisable to take a quality B complex. Look for one that has folate as opposed to folic acid. This bypass absorption issues. I wish you and your husband well.

  20. I bruise very easily with my B12 injections. So I started using the smallest insulin needles and I do one shot in each side instead if using the one bigger needle. It seems to absorb better too when I don't get that big knot at the injection site. I have Celiac, so I guess that's why my B goes so low. Damaged gut.

  21. I was 138 and used magnesium oil plus B12 sub and in a few months I'm now over 800!!! Mine was definitely caused by stress (anxiety and low mag).

  22. Oh and the stress of eating grain, sugar and other crap! Totally eliminated all that out of my life. And I use no chemicals at all. Wishing your hubby all the best x

  23. Nicole Boyd Tepfer + comments

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