Thyroid peroxidase antibodies?


Hi everyone!

I wanted to join for advice from actual people instead of trying to find answers online.
I am also just learning about Hashimoto’s, so please forgive me if you’ve seen this question a million times.
Have any of you successfully lowered your thyroid peroxidase antibodies?
I really want to be proactive with this instead of waiting around for my thyroid to be destroyed.
Please help!

*** Edited to reword question ***
Have any of you stopped the progression of subclinical Hashimoto’s from turning into full-blown Hashimoto’s?

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Gabrielle 3 years 6 Answers 326 views 0

Answers ( 6 )

  1. The antibodies are a serum disease marker and do not tell you anything about the progression of the disease or the severity of symptoms. Some people have very low antibodies with severe symptoms, others have antibodies in the thousands and are symptom free. And then there is a small group of people who have the disease but never present with any antibodies at all. The actual damage to the thyroid gland is done by macrophages and lymphocytes.

  2. Other than the first test, my endo never tested my antibodies after. Basically, it just tells him I have Hashimotos and therefore I am to be treated. My doc was only testing for TSH initially, but I asked that he tested for my free T4 and free T3 because I was not feeling better with the T4 meds. After testing, we both agreed that T3 was needed (mine was very low) and my T4 can be reduced. I feel normalish now with both. But generally, standard endos don’t request those tests, you’d have to ask for them. I am T2 diabetic, so I am following a ketogenic diet to keep my blood sugar low. As such, I have not been around grains and sugar for over 7 years, so that may be helpful since it seems many are on GF diets here. Reducing inflammation is the key for Hashimotos, so you may have to try different things to see what works for you. But getting your meds right is the start.

  3. If you have seronegative Hashimoto’s you have no antibodies, yet you have the disease and your thyroid is still being destroyed. \nAntibodies are just a marker.

  4. Going gluten free soy free and sometimes dairy free can help tremendously and has been known to put hashis into remission so there is ways you can be proactive. Supplements like selenium can help as well.

  5. There was a scientific study that showed that going gluten free did not slow the progression of the disease. My phone is dying, but I’ll try to post it later.

  6. Found it, Suzy!

    At the time of diagnosis, the celiac disease patients had more manifest (n = 7) or subclinical (n = 3) thyroid diseases than the controls (10/27 vs. 3/27, p = 0.055). During the follow-up, the thyroid volume decreased significantly in the patients with celiac disease compared with the controls, indicating the progression of thyroid gland atrophy despite the gluten-free diet.


    Celiac patients had an increased risk of thyroid autoimmune disorders. A gluten-free diet seemed not to prevent the progression of autoimmune process during a follow-up of 1 year.”

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